Centrifugal extraction machine extraction of penicillin purification process is introduced
Penicillin fermentation medium, low per unit volume, fermented liquid after pretreatment and filtering, in the process of production method using centrifugal extraction machine extraction of penicillin purification technology, the use of penicillin in different PH conditions solubility in the water and butyl acetate is different, make the further enrichment and purification of penicillin.
after pretreatment of penicillin fermentation medium in a centrifugal extraction machine and extraction agent for a few seconds to fully mix and high-speed centrifugal separation, thus make penicillin rapidly transferred to butyl acetate phase, shortens the penicillin under acid condition, mixing, separation time, reduced the acid degradation of penicillin, the separation efficiency is greatly increased.
Centrifugal extraction machine extraction of penicillin purification technology, using multi-stage countercurrent extraction, can significantly increase the rate of extraction, and two phase in larger under the action of centrifugal force can be completely separated, only a tiny amount of emulsifier content more than stay in the extraction phase, the yield loss is small, consumption of butyl acetate also reduced accordingly, extract the moisture content is low, less impurity, strong ability to remove impurities, less effect on yield, quality, process after.
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