Chinese medicine chemistry: two-phase solvent extraction operation matters needing attention
by:Deyuan 2020-07-25
in order to help the masses of licensed pharmacists examinee test pass smoothly pass licensed pharmacists, the medical education website small make up to sort out the 'Chinese medicine chemistry: two-phase solvent extraction operation notes' knowledge, relevant content: first, using small tube violent vibration wave about minutes, observe two fluid layer stratification after extraction.
If easy to produce emulsion, a large number of extraction to avoid violent vibration wave, can prolong extraction time.
Such as emulsifying phenomenon, emulsion layer can be separated, then use the new solvent extraction;
Or the emulsion layer suction filter, or heat the emulsion layer slightly;
Or a long time to place does not rotate, make its natural stratification.
Emulsifying phenomenon is serious, can be used in a two-phase solvent reflux extraction plant continuously.
, the concentration of the water extract had better be in proportion.
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Between, is too dilute solvent dosage is too large, affect the operation.
, solvent and aqueous solution should maintain a certain amount, the proportion of extraction for the first time, more solvent, and is commonly/water extract, the dosage of the later can be a bit less, general / -
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, general extraction -
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Time can be.
But hydrophilic hard to turn into larger components organic solvent layer, must increase the extraction times, or change the extraction solvent.