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Medicine material extraction separation equipment in organic synthesis

by:Deyuan      2020-08-12
At present many pharmaceutical companies in the API when organic synthesis using centrifugal extraction with intermediate reaction extraction, solvent extraction and the operation of washing section. API is a set of production process, fermentation - Extraction - Intermediate reaction Extraction - Water - Purification multiple section, such as centrifugal extraction machine is mainly used for extraction and washing section.

with cephalosporin antibiotics, for example, in the process of cefixime production, fermentation, first get mother nucleus, choose corresponding intermediates with mother nuclear reaction, it is concluded that the reaction liquid, choose suitable extractant, the extracting agent compared with the reaction liquid according to certain respectively from different entrance into centrifugal extraction machine, with the aid of the rotation of the drum, through the turbine disc and the impeller to make two phase mixing and dispersing quickly, two phase solution fully mass transfer, mixing and mass transfer process. Mixture again after the effect of drum centrifugal force through two separate out of the body side by side. Subsequent rinsing section still can use the centrifugal extraction machine, will be washed after extraction of organic phase, removing impurity, then continue reaction Extraction - Washed, until they get the final API products.

centrifugal extraction machine applied in the medicine material production and processing of more extensive, mainly machine centrifugal extraction on extraction and washing period of easy operation, high extraction efficiency, and low grade deposit flow, because such products are generally multistage continuous extraction. Centrifugal extraction machine than traditional extraction device, cover an area of an area small, low comprehensive cost, therefore, in medicine extraction industry development prospect is considerable.

if you want to know the detailed operation of centrifugal extraction machine technology and principle, can contact the zhengzhou days extraction technology!
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