Pharmaceutical extraction in the process of drug amantadine pharmaceutical wastewater treatment process
the pharmaceutical production process of organic wastewater is regarded as one of the serious pollution of water environment. The pharmaceutical industry in our country there is a number of enterprises, production scale is small, scattered layout, raw materials into the big but small output, pollution problem. Since 2008, China began to implement the pharmaceutical industrial water pollutant discharge standards. Drainage but most of the enterprise all cannot meet the new emission standards, even if can discharging standard, the operation of the high processing costs also makes the enterprise operation. So looking for a good processing effect, infrastructure and operation cost reasonable technology has become the pharmaceutical wastewater treatment immediate task.
pharmacy is the main pollution sources of organic waste water produced in the process, while the pharmaceutical industry output value accounts for only 117% of the gross value of industrial output, but its wastewater emissions accounted for 2% of the national wastewater. Pharmaceutical industry wastewater mainly have antibiotic wastewater, Chinese traditional medicine wastewater and chemical pharmaceutical wastewater.
is antibiotic pharmaceutical wastewater containing refractory material, biological toxic substances and organic wastewater of high S and N. Antibiotics in screening of antimicrobial in production and production, including breeding, there are still many technical difficulties which appeared low utilization rate of raw materials, low purity and high residual antibiotics content in waste water problems, causing serious pollution of the environment. Antibiotic production including microbial fermentation, filtration, extraction, crystallization, chemical extraction and refining process.
the water quality characteristics of Chinese traditional medicine wastewater is contains saccharides, glycosides, organic pigment, anthraquinone, tannins, alkaloids, cellulose, lignin and other organic matter; SS wastewater is high, including sediment and liquid, and also contains a large amount of debris; The change of COD concentration, and is in commonly 2000 - 6000 mg/L, even in the 100 - Changes between 11000 mg/L; High colority, at about 500 times; The water temperature is 25 - 60℃。
chemical pharmaceutical wastewater treatment of waste water is the water quality characteristic of complex, in addition to containing antibiotics residue, intermediates, unreacted raw materials, also contains a small amount of organic solvents used in the synthesis process. COD concentration of large, generally between 4, 000-4500 mg/L.
extraction amantadine pharmaceutical wastewater treatment
when extracting the complexation extraction process simulation amantadine pharmaceutical wastewater, compared the 11 kinds of extraction agent such as benzene, CCl4 and P204 extraction effect of amantadine in aqueous solution, examines the initial solution pH, the type of the thinner, the ratio of extraction agent and diluent and oil/water ratio on the extraction efficiency and the effect of separation and has carried on the back extraction to extract the research. The results showed that amantadine concentration in aqueous solution is 1000 mg · L - Initial pH value of solution 1, 8. 0 ~ 10. 0, oil/water ratio is 1:1, under the condition of using P204 and octyl alcohol volume 3:2 distribution of extractant in extraction separation, amantadine extraction rate can reach 99. More than 0%, when the concentration of amantadine increased to 10. 0 g·L - 1, the extraction rate can still keep in 97. More than 0%; With 2. 0 mol·L- 1 HCl solution as extraction agent, according to the oil/water ratio of 1:1 to 51. 1% of amantadine extraction separation from the extraction agent.