Traditional Chinese medicine extraction technology of solvent extraction separation of organic acids
Chinese medicine extraction technology of solvent extraction separation of organic acid as a result of the free organic acids ( Except for small molecular weight) Soluble in organic solvents and poorly soluble in water, organic acid salt is soluble in water and soluble in organic solvents, so can let whole organic acid acidification commonly free, then choose a suitable organic solvent extraction. Using the orthogonal experiment optimization xuan papaya total organic acid, with different ethanol concentration on xuan papaya extract, the best extraction technology for ethanol concentration 80%, material liquid than in 25, extraction temperature is 90 ℃, extraction time is 3 h, xuan papaya yield of total organic acids to 10. 46%, which indicates that this process is stable, feasible and suitable for industrial production. Lu prosperous inspection such as low temperature enzyme solution instead of traditional ethanol extraction using auxiliary ethanol reflux extraction of greengage organic acid yield, the results showed that pectinase of greengage digestion ability significantly, the main factors influencing the effect of greengage organic acid extraction for digestion temperature, digestion time, enzyme amount. Greengage organic acids in the appropriate enzyme assisted extraction technological conditions of extraction for the adding quantity of 31. 6 u/mL, enzymolysis temperature 45. 67 ℃, enzymolysis time 3. 41 h, extract the corresponding total organic acid extraction yield of 35. 49%, compared with traditional ethanol reflux extraction yield ( 29. 10%) Have improved significantly.